姓名：毛仁芳
职称：教授
个人简介：河南鹤壁人，医学博士。
专业研究领域：基础医学、病理生理学、血管生物学、淋巴管生物学研究。
专著与论集：
1.jiang yy, lei gy, lin t, et al. 1,6-hexanediol regulates angiogenesis via suppression of cyclin a1-mediated endothelial function. bmc biology. 2023 apr 7;21(1):75.
2.zhou n, zhang y, lei gy, et al. inhibition of bets prevents heat shock-induced cell death via upregulating hsps in sv40 large t antigen transfected cells. genes genomics. 2022, 44(10):1259-1269
3. wu yy, gu hy, bao yh, et al.usp7 sustains an active epigenetic program via stabilizing mll2 and wdr5 in diffuse large b-cell lymphoma. cell biochem funct. 2022, 40(4):379-390.
4. wu yc, yang y, gu hy, et al. multi-omics analysis reveals the functional transcription and potential translation of enhancers. international journal of cancer. 2020, 147(8)：2210-2224.
5. zhu xl, zhang tt, zhang y, et al. a super-enhancer controls tgf- β signaling in pancreatic cancer through downregulation of tgfbr2. cellular signalling.2020, 66: 109470.
6. chen h, zhu xl, sun r, et al. ubiquitin-specific protease 7 is a druggable target that is essential for pancreatic cancer growth and chemoresistance. investigational new drugs. 2020, 38(6):1707-1716.
7. xu yp, wu yc, zhang sl et al. a tumor specific super-enhancer drives immune evasion by guiding synchronous expression of pd-l1 and pd-l2. cell reports. 2019,29(11): 3435-3447.
8. wu yc, tao br, zhang ty et al. pan-cancer analysis reveals disrupted circadian clock associates with t cell exhaustion. frontiers in immunology. 2019, 10: 2451.
9. mao rf, wu yc, ming y et al. enhancer rnas: a missing regulatory layer in gene transcription. sci china life sci. 2019, 62(7):905-912.
10. mao rf, meng s, gu ql et al. aibp limits angiogenesis through r-secretase-mediated upregulation of notch signaling.circulation research, 2017,120: 1727-1739.
11. mao rf, yang ry, chen x et al. regnase-1, a rapid response ribonuclease regulating inflammation and conquering challenges. cellular and molecular immunology.2017, 14, 412-422.
12. mao rf, rubio v, chen hr et al. ola1 protects cells in heat shock by stabilizing hsp70. cell death and disease, 2013, 4: e491.
13. mao rf, fan yh, fu sb et al. tak1 lysine 158 is required for tgf-β-induced traf6-mediated smad-independent ikk/nf-κb and jnk/ap-1 activation. cellular signalling, 2011,23(1): 222-227.
14. mao rf, fan yh, fu sb. association study between methylenetetrahydrofolate reductase gene polymorphisms and graves’ disease. cell biochemistry and function, 2010,28(7): 585-590
15. mao rf, fan yh, jin y et al. methylenetetrahydrofolate reductase gene polymorphisms and lung cancer: a meta-analysis. journal of human genetics, 2008, 53(4): 340-348.
16. mao rf, fan yh, chen f et al. methylenetetrahydrofolate reductase gene polymorphisms in 13 chinese populations. cell biochemistry and function, 2008, 26(3): 352-358.
17. mao rf, fan yh, chen f et al. geneticpolymorphismofmthfr g1793a in chinese populations. european journal of epidemiology, 2008,23(5): 363-368.
主要科研项目
主持多项省部级以上科研项目，其中包括国家自然科学基金项目3项，江苏省自然科学基金1项，江苏省特聘教授基金，美国aha博士后基金。
讲授课程
病理生理学，细胞生物学，科研思维案例教学，高级病理生理学，病理生理学研究进展
指导研究生情况
已毕业硕士生7名（包括联合培养3名）；在读博士生2名，硕士生6名。
